1. Signaling Pathways
  2. Anti-infection
  3. Influenza Virus

Influenza Virus

Influenza virus belongs to the Orthomyxoviridae group, which are enveloped, segmented, single-stranded negative sense RNA viruses. The group includes three types of influenza viruses, A, B and C. Type B and C viruses only infect humans, but the type A viruses infect humans, horses, swine, other mammals, and a wide variety of domesticated and wild birds. Human influenza A and B viruses cause seasonal epidemics of disease almost every winter in the United States. The emergence of a new and very different influenza virus to infect people can cause an influenza pandemic. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-13317S
    Oseltamivir-d3
    Inhibitor 98.61%
    Oseltamivir-d3 is a deuterium labeled Oseltamivir. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent.
    Oseltamivir-d<sub>3</sub>
  • HY-134608
    Cobalt protoporphyrin IX
    Inhibitor
    Cobalt protoporphyrin IX (Co-PPIX) is a potent and specific heme oxygenase-1 (HO-1) inducer. Cobalt protoporphyrin IX exhibits broad-spectrum antiviral activities against Influenza A virus (IAV).
    Cobalt protoporphyrin IX
  • HY-N0191R
    Andrographolide (Standard)
    Inhibitor
    Andrographolide (Standard) is the analytical standard of Andrographolide. This product is intended for research and analytical applications. Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects.
    Andrographolide (Standard)
  • HY-137334
    Neuraminidase-IN-1
    Inhibitor 98.93%
    Neuraminidase-IN-1 is a neuraminidase inhibitor, with an IC50 of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus.
    Neuraminidase-IN-1
  • HY-135810A
    Cletoquine oxalate
    Inhibitor 99.76%
    Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine. Cletoquine oxalate is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine oxalate is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine oxalate has antimalarial effects and has the potential for autoimmune diseases treatment.
    Cletoquine oxalate
  • HY-N5056
    DL-Goitrin
    99.79%
    DL-Goitrin, also called (R, S)- report by the spring, consists of the epigoitrin (reported by the R- Spring) and the spring (-S- reported by spring), and the two mutually isomers, and the mixture is the ingredient of cruciferous vegetables.
    DL-Goitrin
  • HY-136559
    6-Azathymine
    Inhibitor 99.94%
    6-Azathymine, a 6-nitrogen analog of thymine, is a potent D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor. 6-Azathymine inhibits the biosynthesis of DNA, and has antibacterial and antiviral activities.
    6-Azathymine
  • HY-20685S
    Palmitoylethanolamide-d4
    Inhibitor ≥99.0%
    Palmitoylethanolamide-d4 is the deuterium labeled Palmitoylethanolamide. Palmitoylethanolamide (Palmidrol) is an active endogenous compound which can used for preventing virus infection of the respiratory tract.
    Palmitoylethanolamide-d<sub>4</sub>
  • HY-P1783A
    M2e, human TFA
    99.86%
    M2e, human TFA, consisting of the 23 extracellular residues of M2 (the third integral membrane protein of influenza A), has been remarkably conserved in all human influenza A. M2e, human TFA is a valid and versatile vaccine candidate to protect against any strain of human influenza A.
    M2e, human TFA
  • HY-N0453R
    Hypericin (Standard)
    Inhibitor
    Hypericin (Standard) is the analytical standard of Hypericin. This product is intended for research and analytical applications. Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis.
    Hypericin (Standard)
  • HY-I0400S3
    N-Acetylneuraminic acid-13C-3
    ≥99.0%
    N-Acetylneuraminic acid-13C-3 is the 13C labeled N-Acetylneuraminic acid.
    N-Acetylneuraminic acid-<sup>13</sup>C-3
  • HY-W130965
    1-Formyl-beta-carboline
    Inhibitor 99.70%
    1-Formyl-beta-carboline is an alkaloid with inhibitory activity against Newcastle disease virus (NDV). 1-Formyl-beta-carboline can effectively inhibit different genotypes of NDV with IC50 values within 10 μM, and its inhibition rate is more than 90% at a concentration of 20 μM. 1-Formyl-beta-carboline mainly exerts its effects by inhibiting the adsorption and entry processes in the NDV life cycle. 1-Formyl-beta-carboline has been identified as a novel HN inhibitor that can directly interact with the NDV HN protein and affect the adsorption of NDV. 1-Formyl-beta-carboline also inhibits the entry of NDV by inhibiting the PI3K/Akt signaling pathway rather than the ERK pathway.
    1-Formyl-beta-carboline
  • HY-B0510B
    Trimethoprim hydrochloride
    Inhibitor 99.16%
    Trimethoprim hydrochloride is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim hydrochloride is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim hydrochloride has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim hydrochloride can inhibit infection of Influenza A virus in chick embryo when combinated with zinc.
    Trimethoprim hydrochloride
  • HY-P1407
    Z-VRPR-FMK TFA
    Inhibitor
    Z-VRPR-FMK (TFA) (VRPR), a tetrapeptide, is a selective and irreversible MALT1 (Mucosa-associated lymphoid tissue lymphoma translocation protein 1) inhibitor. Z-VRPR-FMK (TFA) can protect against influenza A virus (IAV) infection.
    Z-VRPR-FMK TFA
  • HY-P1788
    Influenza A NP(366-374) Strain A/PR/8/35
    99.81%
    Influenza A NP(366-374) Strain A/PR/8/35 is an H2-Db-restricted epitope from Influenza A/PR/8/35 nucleoprotein.
    Influenza A NP(366-374) Strain A/PR/8/35
  • HY-N0898S
    Catechin-13C3
    Inhibitor 98.06%
    Catechin-13C3 is the 13C-labeled Catechin. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
    Catechin-<sup>13</sup>C<sub>3</sub>
  • HY-N6055
    Nuezhenidic acid
    99.56%
    Nuezhenidic acid can be isolated from the fruits of Ligustrum lucidum, posseses inhibitory activities against influenza A virus.
    Nuezhenidic acid
  • HY-113512
    17-HDHA
    Inhibitor 98.8%
    17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27+ CD38+ antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells.
    17-HDHA
  • HY-W709856
    Dodeca-2E,4E,8Z,10Z/E-N-tetraenoic acid isobutylamide
    98.54%
    Dodeca-2E,4E,8Z,10Z/E-N-tetraenoic acid isobutylamide is a brain-penetrant substance and the main alkamide in Echinacea preparations, which might be used for research of common cold and various upper respiratory infections.
    Dodeca-2E,4E,8Z,10Z/E-N-tetraenoic acid isobutylamide
  • HY-N2011R
    Octyl gallate (Standard)
    Inhibitor
    Octyl gallate (Standard) is the analytical standard of Octyl gallate. This product is intended for research and analytical applications. Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity. Octyl gallate (Progallin O) shows selective and sensitive fluorescent property. Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus.
    Octyl gallate (Standard)
Cat. No. Product Name / Synonyms Species Source
Cat. No. Product Name / Synonyms Application Reactivity