2. Signaling Pathways
  3. Anti-infection
  4. Influenza Virus

Influenza Virus

Influenza Virus

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Influenza virus belongs to the Orthomyxoviridae group, which are enveloped, segmented, single-stranded negative sense RNA viruses. The group includes three types of influenza viruses, A, B and C. Type B and C viruses only infect humans, but the type A viruses infect humans, horses, swine, other mammals, and a wide variety of domesticated and wild birds. Human influenza A and B viruses cause seasonal epidemics of disease almost every winter in the United States. The emergence of a new and very different influenza virus to infect people can cause an influenza pandemic. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N3035
    Tetrahydroepiberberine
    		Inhibitor 99.20%
    Tetrahydroepiberberine is a isoquinoline alkaloid isolated from Corydalis impatiens (Pall). Tetrahydroepiberberine has antifungal and selective inhibition against the PI-3 virus activities.
    Tetrahydroepiberberine
  • HY-113512
    17-HDHA
    		Inhibitor 98.8%
    17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27+ CD38+ antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells.
    17-HDHA
  • HY-W269306
    Bonaphthone
    		Inhibitor
    Bonaphthone is an antiviral agent with anti-DNA and -RNA viral activities.
    Bonaphthone
  • HY-N0683R
    α-Vitamin E (Standard)
    		Inhibitor
    α-Vitamin E (Standard) is the analytical standard of α-Vitamin E. This product is intended for research and analytical applications. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant.
    α-Vitamin E (Standard)
  • HY-W709856
    Dodeca-2E,4E,8Z,10Z/E-N-tetraenoic acid isobutylamide
    		98.54%
    Dodeca-2E,4E,8Z,10Z/E-N-tetraenoic acid isobutylamide is a brain-penetrant substance and the main alkamide in Echinacea preparations, which might be used for research of common cold and various upper respiratory infections.
    Dodeca-2E,4E,8Z,10Z/E-N-tetraenoic acid isobutylamide
  • HY-B0217S
    Nitazoxanide-d4
    		Inhibitor 99.78%
    Nitazoxanide-d4 is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.
    Nitazoxanide-d<sub>4</sub>
  • HY-135853S
    Molnupiravir-d7
    		Inhibitor 99.86%
    Molnupiravir-d7 is the deuterium labeled Molnupiravir. Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza.
    Molnupiravir-d<sub>7</sub>
  • HY-131059
    CBS1117
    		Inhibitor 99.76%
    CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A virus, A/Puerto Rico/8/34 (H1N1). CBS1117 interferes with the hemagglutinin (HA)-mediated fusion process.
    CBS1117
  • HY-131179
    Influenza A virus-IN-1
    		Inhibitor 99.88%
    Influenza A virus-IN-1 is a dihydropyrrolidones derivative and is a potent inhibitor against wide subtypes of influenza A virus (IAV) with IC50 values from 3.11 μM to 7.13 μM. Influenza A virus-IN-1 efficiently inhibits replication of IAV, up-regulates the expression of key antiviral cytokines IFN-β and antiviral protein MxA.
    Influenza A virus-IN-1
  • HY-W013794
    Salcomine
    		Inhibitor 99.10%
    Salcomine (N,N’-Bis(salicylidene)ethylenediaminocobalt II) is a carrier of O2 and oxidation catalysts. Salcomine has anti-influenza virus activity.
    Salcomine
  • HY-13317S
    Oseltamivir-d3
    		Inhibitor 98.61%
    Oseltamivir-d3 is a deuterium labeled Oseltamivir. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent.
    Oseltamivir-d<sub>3</sub>
  • HY-137334
    Neuraminidase-IN-1
    		Inhibitor 98.93%
    Neuraminidase-IN-1 is a neuraminidase inhibitor, with an IC50 of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus.
    Neuraminidase-IN-1
  • HY-N5056
    DL-Goitrin
    		99.79%
    DL-Goitrin, also called (R, S)- report by the spring, consists of the epigoitrin (reported by the R- Spring) and the spring (-S- reported by spring), and the two mutually isomers, and the mixture is the ingredient of cruciferous vegetables.
    DL-Goitrin
  • HY-N11630
    Pinellic acid
    		Inhibitor ≥99.0%
    Pinellic acid is a natural product that could be isolated from a medicinal plant Pinelliae tuber. Pinellic acid is an effective oral adjuvant for nasal influenza vaccine.
    Pinellic acid
  • HY-136559
    6-Azathymine
    		Inhibitor 99.94%
    6-Azathymine, a 6-nitrogen analog of thymine, is a potent D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor. 6-Azathymine inhibits the biosynthesis of DNA, and has antibacterial and antiviral activities.
    6-Azathymine
  • HY-B0272S2
    Rifampicin-d4
    		Inhibitor 99.69%
    Rifampicin-d4 is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.
    Rifampicin-d<sub>4</sub>
  • HY-P1783A
    M2e, human TFA
    		99.86%
    M2e, human TFA, consisting of the 23 extracellular residues of M2 (the third integral membrane protein of influenza A), has been remarkably conserved in all human influenza A. M2e, human TFA is a valid and versatile vaccine candidate to protect against any strain of human influenza A.
    M2e, human TFA
  • HY-B0510B
    Trimethoprim hydrochloride
    		Inhibitor 99.16%
    Trimethoprim hydrochloride is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim hydrochloride is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim hydrochloride has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim hydrochloride can inhibit infection of Influenza A virus in chick embryo when combinated with zinc.
    Trimethoprim hydrochloride
  • HY-P1407
    Z-VRPR-FMK TFA
    		Inhibitor
    Z-VRPR-FMK (TFA) (VRPR), a tetrapeptide, is a selective and irreversible MALT1 (Mucosa-associated lymphoid tissue lymphoma translocation protein 1) inhibitor. Z-VRPR-FMK (TFA) can protect against influenza A virus (IAV) infection.
    Z-VRPR-FMK TFA
  • HY-N0898S
    Catechin-13C3
    		Inhibitor 98.06%
    Catechin-13C3 is the 13C-labeled Catechin. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
    Catechin-<sup>13</sup>C<sub>3</sub>
Cat. No. Product Name / Synonyms Species Source
Cat. No. Product Name / Synonyms Application Reactivity